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Nicola Gaibazzi, Filippo Pigazzani, Claudio Reverberi, and Thomas R Porter

Introduction Noninvasive identification of patients with coronary artery disease (CAD) remains a clinical challenge despite the widespread use, and possible overuse, of imaging and provocative testing; more than 50% of patients currently

Open access

Arzu Cubukcu, Ian Murray, and Simon Anderson

typical or atypical angina symptoms be referred for further investigation, in the form of functional imaging and/or coronary angiography (1) . Based on research by Pryor et al . (2) , an estimated risk of coronary artery disease (CAD) is determined

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Maria Pia Donataccio, Claudio Reverberi, and Nicola Gaibazzi

Background The combination of myocardial perfusion (MP) imaging and dipyridamole or dobutamine real-time contrast echocardiography improves the sensitivity to detect coronary artery disease (CAD), particularly multivessel CAD. Patients with diffused

Open access

Theodoros Ntoskas, Farhanda Ahmad, and Paul Woodmansey

findings with significant CAD in one, two or three vessels. In five cases (19.2%), the diagnostic angiogram revealed unobstructed epicardial coronary arteries. Eight of 239 patients (3.3%) with negative DSE for ischaemia, subsequently had a coronary

Open access

Apostolos Vrettos, David Dawson, Chrysanthos Grigoratos, and Petros Nihoyannopoulos

Introduction Percutaneous coronary intervention with TAXUS and cardiac surgery known as SYNTAX score (SS) is an angiographic tool used to determine the severity of coronary artery disease (CAD) in patients undergoing coronary angiography. Two

Open access

Camelia Demetrescu, Shelley Rahman Haley, and Aigul Baltabaeva

with HCM may also have atherosclerotic coronary artery disease (CAD). Reports on the prevalence of CAD in HCM have varied, but up to 20% of adult HCM patients over the age of 45 years have been shown to have coexistent CAD ( 7 ). Severe epicardial CAD

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Benoy N Shah and Roxy Senior

necessary to exclude coronary artery disease (CAD) as a possible underlying cause (e.g. angina equivalent as a cause of dyspnea). The body habitus of such patients often poses significant technical challenges for each of the noninvasive imaging techniques

Open access

Victoria Pettemerides, Thomas Turner, Conor Steele, and Anita Macnab

recommended by the National Institute of Clinical Excellence (NICE) as the initial investigation for patients presenting with suspected coronary artery disease (CAD) and an intermediate pre-test probability (PTP). As a result, functional imaging modalities

Open access

Alexandros Papachristidis, Damian Roper, Daniela Cassar Demarco, Ioannis Tsironis, Michael Papitsas, Jonathan Byrne, Khaled Alfakih, and Mark J Monaghan

coronary artery disease (CAD) ( 2 ), valvular heart disease ( 3 ), pre-operative assessment ( 4 ) and in the assessment of myocardial viability ( 5 ). The guidelines have recommended the use of imaging functional tests in the diagnosis of intermediate

Open access

Lijun Qian, Feng Xie, Di Xu, and Thomas R Porter

Introduction Suspected symptomatic coronary artery disease (CAD) is a common reason for referral to an emergency department (ED) or outpatient clinic ( 1 ). Although standardized clinical risk scores utilizing EKG and biomarker data are